WOW Addons and Vista
Have seen quite a few searches by people having problems running World of Warcraft while running under Windows Vista, so I am dedicating a post just for that. They mostly concern running world of warcraft mods and addons.
From all that I have read, if WOW is installed in your program files folder, it can cause problems with Windows Vista because of some caching that can mess it up. For best results, install WOW outside of your program files folder. Also, make sure the addons are still enabled in the Blizzard UI by clicking on the addons button.
It should not matter what your OS is, this should have no affect on your addons or other WOW mods, unless you have had to re-install them. As you may have noticed using Windows XP, when you use the Windows zip program, the default behavior is to expand the files into a folder of the same name. So, if you are extracting a folder called CT Raid, it will actually extract it into another folder called CT Raid. So, if WOW is looking inside the CT Raid folder, it will only see another folder called CT Raid, it will not see any of the required files. So, this could be part of the problem users are having. When installing addons, it would probably be best to extract the zip files into My Documents and then copy over the actual folder with the programs to the addons folder, thus avoiding any of the extra folders.
There are also some issues posted on the WOW Forums concerning Windows Vista:
Vista may do a few things that are out of the ordinary when you installed it in the C:\Program Files\ or C:\Program Files (x86) folders – it may either not apply your settings or it won’t delete them properly.
* Resetting settings or settings that does not apply properly – Vista may deny you write access from the World of Warcraft folder if it is installed in the Program Files folder. You can remedy this by either right-clicking the game and selecting “Run as administrator” or to move it outside of the Program Files folder.
* Settings and mods that won’t stay deleted – If you installed the game in the Program Files folder, Vista may redirect the game to look in another set of folders: c:\Users\
\AppData\Local\VirtualStore\Program Files\World of Warcraft\
It will save all of your custom configurations there instead of the C:\Program Files\World of Warcraft folder. You can delete your settings by going to the folder above or moving the game outside of the World of Warcraft folder. Source: Windows Vista from the WOW Forums